Insular cortex hypoperfusion and acute phase blood glucose after stroke: a CT perfusion study

<p><b>Background and Purpose:</b> Insular cortex ischemia is proposed to mediate a sympathetic stimulus that leads to acute hyperglycemia after stroke.</p> <p><b>Methods:</b> We retrospectively analyzed insular perfusion on perfusion CT (median 180 minutes after onset) in 35 patients.</p> <p><b>Results:</b> We found no association of hypoperfusion (relative cerebral blood flow <0.51) with early (<6 hours) or delayed (<72 hours) hyperglycemia, or hemispheric lateralization.</p> <p><b>Conclusions:</b> Insular cortex hypoperfusion <6 hours after stroke onset was not associated with hyperglycemia.</p&gt